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Gene

zbtb16b

ID
ZDB-GENE-100923-1
Name
zinc finger and BTB domain containing 16b
Symbol
zbtb16b Nomenclature History
Previous Names
  • plzfb (1)
  • wu:fb53a11
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of type I interferon production. Located in nucleus. Is expressed in several structures, including anterior neural keel; atrium; hindbrain neural keel; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zbtb16b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukemia, acute promyelocytic, PL2F/RARA type
Skeletal defects, genital hypoplasia, and mental retardation 612447
Associated With zbtb16b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain SKP1/BTB/POZ domain superfamily Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:E7FGS1 659
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations