Gene
znf574
- ID
- ZDB-GENE-100922-259
- Name
- zinc finger protein 574
- Symbol
- znf574 Nomenclature History
- Previous Names
-
- rumba (1)
- si:ch211-87d12.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within definitive hemopoiesis. Predicted to be located in nucleus. Is expressed widely. Orthologous to several human genes including ZNF662 (zinc finger protein 662); ZNF667 (zinc finger protein 667); and ZNF671 (zinc finger protein 671).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Du et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Du et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
| UniProtKB:F1QUN0 | InterPro | 1008 | ||
| UniProtKB:D2KMS9 | InterPro | 1009 | ||
| UniProtKB:A0A8M9P821 | InterPro | 1006 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
znf574-201
(1)
|
Ensembl | 3,102 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-87D12 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-67N17 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001170836 (1) | 3105 nt | ||
| Genomic | GenBank:BX005242 (1) | 192177 nt | ||
| Polypeptide | UniProtKB:D2KMS9 (1) | 1009 aa |
- Zhang, L., Fang, Y., Lu, X., Xu, S., Cai, F., Yu, M., Li, X., Zhong, S. (2020) Transcriptional response of zebrafish larvae exposed to lindane reveals two detoxification genes of ABC transporter family (abcg5 and abcg8). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 232:108755
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Du, L., Xu, J., Li, X., Ma, N., Liu, Y., Peng, J., Osato, M., Zhang, W., and Wen, Z. (2011) Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis. Development (Cambridge, England). 138(4):619-629
1 - 3 of 3
Show