ZFIN ID: ZDB-GENE-100922-256
Gene Name: Rho GTPase activating protein 31
Gene Symbol: arhgap31    Nomenclature History

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Previous Name: si:dkey-70b23.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to localize to lamellipodium. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human ARHGAP31 (Rho GTPase activating protein 31).
Genome Resources: Alliance (1),  Gene:101885883 (1),  Ensembl(GRCz11):ENSDARG00000059472 (2)
GENE EXPRESSION
All Expression Data: Fig. 3 from Gomez et al., 2012
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20586 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arhgap31 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Adams-Oliver syndrome Alliance Adams-Oliver syndrome 1 100300
    DISEASE ASSOCIATED WITH arhgap31 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component lamellipodium (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arhgap31-201 (1)    Ensembl 4378
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgap31 No data available
    MARKER RELATIONSHIPS
    arhgap31 Contained in: [BAC] DKEY-70B23 (1) (order this)
    [Fosmid] CH1073-177A15 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005165631 (1)
    Genomic GenBank:CU137652 (1) 194527 nt
    Select Tool
    Polypeptide UniProtKB:E9QGF9 (1) 1391 aa
    Sequence Information (all 11)
    ORTHOLOGY for arhgap31 ( Chr: 5 )
    CITATIONS (16)