Gene

dus2

ID

ZDB-GENE-100922-233

Name

dihydrouridine synthase 2

Symbol

dus2 Nomenclature History

Previous Names

dus2l
si:ch73-46g7.4

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have RNA binding activity; flavin adenine dinucleotide binding activity; and tRNA dihydrouridine synthase activity. Predicted to be involved in oxidation-reduction process and tRNA processing. Orthologous to human DUS2 (dihydrouridine synthase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dus2 Human Ortholog

No data available

Associated With dus2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018517	tRNA-dihydrouridine synthase, conserved site
Domain	IPR014720	Double-stranded RNA-binding domain
Domain	IPR035587	DUS-like, FMN-binding domain
Domain	IPR044463	DUS2, double-stranded RNA binding domain
Family	IPR052582	tRNA-dihydrouridine synthase-like
Homologous_superfamily	IPR013785	Aldolase-type TIM barrel

Domain Details Per Protein

Protein	Length	Aldolase-type TIM barrel	Double-stranded RNA-binding domain	DUS2, double-stranded RNA binding domain	DUS-like, FMN-binding domain	tRNA-dihydrouridine synthase, conserved site	tRNA-dihydrouridine synthase-like
UniProtKB:E7F220 InterPro	504

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	dus2-201 (1) Ensembl	Ensembl	826 nt	Select Tool
mRNA	dus2-204 (1) Ensembl	Ensembl	1,942 nt	Select Tool
mRNA	dus2-206 (1) Ensembl	Ensembl	490 nt	Select Tool
mRNA	dus2-207 (1) Ensembl	Ensembl	2,294 nt	Select Tool ZFIN BLAST
ncRNA	dus2-002 (1) Ensembl	Ensembl	520 nt	Select Tool
ncRNA	dus2-005 (1) Ensembl	Ensembl	721 nt	Select Tool
ncRNA	dus2-006 (1) Ensembl	Ensembl	629 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations