Gene

rubcn

ID
ZDB-GENE-100922-142
Name
rubicon autophagy regulator
Symbol
rubcn Nomenclature History
Previous Names
  • si:ch1073-167a23.1
  • si:ch1073-280h16.1
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol phosphate binding activity. Predicted to be involved in negative regulation of autophagosome maturation; negative regulation of endocytosis; and negative regulation of phosphatidylinositol 3-kinase activity. Predicted to localize to early endosome; intracellular membrane-bounded organelle; and late endosome. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 15. Orthologous to human RUBCN (rubicon autophagy regulator).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rubcn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 15 Alliance Spinocerebellar ataxia, autosomal recessive 15 615705
Associated With rubcn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004012 RUN domain
Domain IPR025258 Putative zinc-RING and/or ribbon
Homologous_superfamily IPR037213 RUN domain superfamily
Domain Details Per Protein
Protein Length Putative zinc-RING and/or ribbon RUN domain RUN domain superfamily
UniProtKB:A0A2R8RJG6 905
UniProtKB:A0A2R8QKK4 940
UniProtKB:F1Q4W5 914
UniProtKB:A0A2R8Q663 956
UniProtKB:A0A0N5E8A0 930
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations