ZFIN ID: ZDB-GENE-100922-123
Gene Name: urotensin-2 receptor 3
Gene Symbol: uts2r3    Nomenclature History

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Previous Names: uts2ra (1), si:dkey-27n14.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have urotensin II receptor activity. Involved in skeletal system development. Predicted to localize to the integral component of plasma membrane. Used to study idiopathic scoliosis. Is expressed in myotome and somite.
Genome Resources: Alliance (1),  Gene:795198 (1),  Ensembl(GRCz11):ENSDARG00000040816 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ouc2014 Indel Unknown Unknown TALEN
sa6418 Point Mutation Unknown Premature Stop ENU
sa16966 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-uts2r3 N/A 1
    MO2-uts2r3 N/A 1
    TALEN1-uts2r3 1
    DISEASE ASSOCIATED WITH uts2r3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH uts2r3 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    idiopathic scoliosis uts2r3ouc2014/ouc2014 standard conditions Zhang et al., 2018
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process skeletal system development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function G protein-coupled receptor activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000276 G protein-coupled receptor, rhodopsin-like
    Domain IPR017452 GPCR, rhodopsin-like, 7TM
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:dkey-27n14.1-201 (1)    Ensembl 1906
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uts2r3 No data available
    MARKER RELATIONSHIPS
    uts2r3 Contained in: [BAC] DKEY-27N14 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005157928 (1) 1817 bp
    Genomic GenBank:BX322544 (1) 102811 bp
    Select Tool
    Polypeptide UniProtKB:F1QSR0 (1) 386 aa
    Sequence Information (all 4)
    ORTHOLOGY for uts2r3 ( Chr: 16 )
    CITATIONS (13)