ZFIN ID: ZDB-GENE-100921-43
Gene Name: bromodomain and WD repeat domain containing 3
Gene Symbol: brwd3    Nomenclature History

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Previous Name: si:dkey-237j10.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human BRWD3 (bromodomain and WD repeat domain containing 3).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000035540 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-brwd3 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH brwd3 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability Alliance Mental retardation, X-linked 93 300659
DISEASE ASSOCIATED WITH brwd3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cytoskeleton organization (more)
Cellular Component nucleus (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA brwd3-202 (1)    Ensembl 3235
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM brwd3 No data available
MARKER RELATIONSHIPS
brwd3 Contained in: [BAC] DKEY-237J10 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:CR762398 188292 nt
Select Tool
Polypeptide UniProtKB:F1QEQ5 (1) 1624 aa
Sequence Information (all 3)
ORTHOLOGY for brwd3 ( Chr: 5 )
CITATIONS (14)