Gene

brwd3

ID
ZDB-GENE-100921-43
Name
bromodomain and WD repeat domain containing 3
Symbol
brwd3 Nomenclature History
Previous Names
  • si:dkey-237j10.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human BRWD3 (bromodomain and WD repeat domain containing 3).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brwd3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability 93 Alliance Mental retardation, X-linked 93 300659
Associated With brwd3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001487 Bromodomain
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Bromodomain Bromodomain, conserved site Bromodomain-like superfamily WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E9QBL4 1046
UniProtKB:F1QEQ5 1624
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations