Gene
kalrna
- ID
- ZDB-GENE-100921-4
- Name
- kalirin RhoGEF kinase a
- Symbol
- kalrna Nomenclature History
- Previous Names
-
- si:dkey-275m12.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in hemopoiesis. Is expressed in head. Orthologous to human KALRN (kalirin RhoGEF kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sarangdhar et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Bielczyk-Maczyńska et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001251 | CRAL-TRIO lipid binding domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR028570 | Kalirin/Triple functional domain protein, SH3 domain 1 |
| Domain | IPR047053 | Kalirin/Triple functional domain protein, SH3 domain 2 |
| Domain | IPR047054 | Kalirin/Triple functional domain protein, pleckstrin homology (PH) domain 1 |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR036865 | CRAL-TRIO lipid binding domain superfamily |
| Repeat | IPR002017 | Spectrin repeat |
| Repeat | IPR018159 | Spectrin/alpha-actinin |
Domain Details Per Protein
| Protein | Length | CRAL-TRIO lipid binding domain | CRAL-TRIO lipid binding domain superfamily | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype | Immunoglobulin subtype 2 | Kalirin/Triple functional domain protein, pleckstrin homology (PH) domain 1 | Kalirin/Triple functional domain protein, SH3 domain 1 | Kalirin/Triple functional domain protein, SH3 domain 2 | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | SH3 domain | SH3-like domain superfamily | Spectrin/alpha-actinin | Spectrin repeat |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3BC94
|
1283 | |||||||||||||||||||||||||
|
UniProtKB:A0A8M3B5D5
|
2967 | |||||||||||||||||||||||||
|
UniProtKB:A0A8M9QFR7
|
2966 | |||||||||||||||||||||||||
|
UniProtKB:A0A8M3AVQ1
|
1353 | |||||||||||||||||||||||||
|
UniProtKB:A0A8M3B2F5
|
2936 | |||||||||||||||||||||||||
|
UniProtKB:A0A8M6Z2L7
|
2968 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
kalrna-202
(1)
|
Havana | 7269 nt |
Interactions and Pathways
No data available
Plasmids
No data available