ZFIN ID: ZDB-GENE-100805-4
Gene Name: natriuretic peptide receptor 1b
Gene Symbol: npr1b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to localize to plasma membrane. Is expressed in several structures, including eye; fin; integument; muscle; and renal system. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1).
Genome Resources: Alliance (1),  Gene:555911 (1),  Ensembl(GRCz11):ENSDARG00000018750 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012911Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019688Tg Transgenic Insertion Unknown Unknown DNA
    sa12864 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16937 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44853 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH npr1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH npr1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process olfactory bulb axon guidance (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA npr1b-202 (1)    Ensembl 3317
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM npr1b No data available
    MARKER RELATIONSHIPS
    npr1b Contained in: [BAC] DKEY-202I12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009292394 (1)
    Genomic GenBank:CR848841 (1) 205755 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F3T9 (1) 1070 aa
    Sequence Information (all 7)
    ORTHOLOGY for npr1b ( Chr: 16 )
    CITATIONS (23)