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Gene

adcy1b

ID
ZDB-GENE-100805-1
Name
adenylate cyclase 1b
Symbol
adcy1b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable adenylate cyclase activity. Acts upstream of or within axon midline choice point recognition; retinal ganglion cell axon guidance; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Santos-Cortez et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adcy1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 44 Alliance ?Deafness, autosomal recessive 44 610154
Associated With adcy1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
Domain IPR009398 Adenylate cyclase, conserved domain
Domain IPR032628 Adenylate cyclase, N-terminal
Family IPR030672 Adenylate cyclase
Homologous_superfamily IPR029787 Nucleotide cyclase
Domain Details Per Protein
Protein Length Adenylate cyclase Adenylate cyclase, conserved domain Adenylate cyclase, N-terminal Adenylyl cyclase class-3/4/guanylyl cyclase Adenylyl cyclase class-4/guanylyl cyclase, conserved site Nucleotide cyclase
UniProtKB:F1R914 834
UniProtKB:X1WFI2 506
UniProtKB:D1MIA3 1114
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations