ZFIN ID: ZDB-GENE-100624-1
Gene Name: dedicator of cytokinesis 3
Gene Symbol: dock3    Nomenclature History

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Previous Name: si:ch211-216d10.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human DOCK3 (dedicator of cytokinesis 3).
Genome Resources: Alliance (1),  Gene:100536057 (1),  Ensembl(GRCz11):ENSDARG00000063180 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dock3 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia 618292
DISEASE ASSOCIATED WITH dock3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process small GTPase mediated signal transduction (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA dock3-204 (1)    Ensembl 5155
dock3-205 (1)    Ensembl 726
ncRNA dock3-003 (1)    Ensembl 683
dock3-004 (1)    Ensembl 539
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM dock3 No data available
MARKER RELATIONSHIPS
dock3 Contained in: [BAC] CH73-65J9 (1), CH73-360P21 (1), CH211-216D10 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_009296479 (1)
Genomic GenBank:CT033817 (1) 211571 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1QDP8 (1) 1990 aa
Sequence Information (all 42)
ORTHOLOGY for dock3 ( Chr: 22 )
CITATIONS (19)