Gene

washc4

ID
ZDB-GENE-100427-4
Name
WASH complex subunit 4
Symbol
washc4 Nomenclature History
Previous Names
  • gb:eb910990 (1)
  • si:dkey-23p11.2 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Involved in regulation of autophagy. Predicted to localize to WASH complex and endosome. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human WASHC4 (WASH complex subunit 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Kustermann et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Kustermann et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With washc4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive non-syndromic intellectual disability Alliance ?Mental retardation, autosomal recessive 43 615817
Associated With washc4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR028191 WASH complex subunit 7, N-terminal
Domain IPR028282 WASH complex subunit 7, central domain
Domain IPR028283 WASH complex subunit 7, C-terminal
Family IPR027307 WASH complex subunit 7
Domain Details Per Protein
Protein Length WASH complex subunit 7 WASH complex subunit 7, central domain WASH complex subunit 7, C-terminal WASH complex subunit 7, N-terminal
UniProtKB:E7F4L4 1173
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations