Gene
aldh1l2
- ID
- ZDB-GENE-100426-6
- Name
- aldehyde dehydrogenase 1 family, member L2
- Symbol
- aldh1l2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have aldehyde dehydrogenase (NAD+) activity and formyltetrahydrofolate dehydrogenase activity. Predicted to be involved in several processes, including 10-formyltetrahydrofolate catabolic process; biosynthetic process; and one-carbon metabolic process. Predicted to localize to mitochondrion. Orthologous to human ALDH1L2 (aldehyde dehydrogenase 1 family member L2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR001555 | Phosphoribosylglycinamide formyltransferase, active site |
Conserved_site | IPR016160 | Aldehyde dehydrogenase, cysteine active site |
Conserved_site | IPR029510 | Aldehyde dehydrogenase, glutamic acid active site |
Domain | IPR002376 | Formyl transferase, N-terminal |
Domain | IPR005793 | Formyl transferase, C-terminal |
Domain | IPR009081 | Phosphopantetheine binding ACP domain |
Domain | IPR015590 | Aldehyde dehydrogenase domain |
Family | IPR011407 | 10-formyltetrahydrofolate dehydrogenase |
Homologous_superfamily | IPR011034 | Formyl transferase-like, C-terminal domain superfamily |
Homologous_superfamily | IPR016161 | Aldehyde/histidinol dehydrogenase |
Homologous_superfamily | IPR016162 | Aldehyde dehydrogenase, N-terminal |
Homologous_superfamily | IPR016163 | Aldehyde dehydrogenase, C-terminal |
Homologous_superfamily | IPR036477 | Formyl transferase, N-terminal domain superfamily |
Homologous_superfamily | IPR036736 | ACP-like superfamily |
Homologous_superfamily | IPR037022 | Formyl transferase, C-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | 10-formyltetrahydrofolate dehydrogenase | ACP-like superfamily | Aldehyde dehydrogenase, C-terminal | Aldehyde dehydrogenase, cysteine active site | Aldehyde dehydrogenase domain | Aldehyde dehydrogenase, glutamic acid active site | Aldehyde dehydrogenase, N-terminal | Aldehyde/histidinol dehydrogenase | Formyl transferase, C-terminal | Formyl transferase, C-terminal domain superfamily | Formyl transferase-like, C-terminal domain superfamily | Formyl transferase, N-terminal | Formyl transferase, N-terminal domain superfamily | Phosphopantetheine binding ACP domain | Phosphoribosylglycinamide formyltransferase, active site |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M1RK21
|
923 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
aldh1l2-201
(1)
|
Havana | 3053 nt | |
mRNA |
aldh1l2-202
(1)
|
Havana | 853 nt |
Interactions and Pathways
No data available
Plasmids
No data available