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Gene

cacna2d4b

ID
ZDB-GENE-100422-18
Name
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
Symbol
cacna2d4b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable voltage-gated calcium channel activity. Acts upstream of or within retinal cone cell development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated calcium channel complex. Is expressed in cerebellum; retinal inner nuclear layer; and retinal outer nuclear layer. Orthologous to human CACNA2D4 (calcium voltage-gated channel auxiliary subunit alpha2delta 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Schlegel et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cacna2d4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cone dystrophy Alliance Retinal cone dystrophy 4 610478
Associated With cacna2d4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR013608 VWA N-terminal
Domain IPR013680 Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region von Willebrand factor A-like domain superfamily von Willebrand factor, type A VWA N-terminal
UniProtKB:A0A2R8RJ74 98
UniProtKB:F1QYJ5 1087
UniProtKB:A0A286Y847 933
UniProtKB:A0A2R8QD87 760
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations