Gene

ccdc88c

ID
ZDB-GENE-100419-3
Name
coiled-coil domain containing 88C
Symbol
ccdc88c Nomenclature History
Previous Names
  • zDAPLE (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have G-protein alpha-subunit binding activity; dynein light intermediate chain binding activity; and microtubule binding activity. Predicted to be involved in apical constriction; cytoplasmic microtubule organization; and cytoskeleton-dependent intracellular transport. Predicted to localize to cell junction; centrosome; and cytoplasm. Human ortholog(s) of this gene implicated in hydrocephalus and spinocerebellar ataxia type 40. Orthologous to human CCDC88C (coiled-coil domain containing 88C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Marivin et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Marivin et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccdc88c Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hydrocephalus Alliance Hydrocephalus, congenital, 1 236600
spinocerebellar ataxia type 40 Alliance ?Spinocerebellar ataxia 40 616053
Associated With ccdc88c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001715 Calponin homology domain
Domain IPR043936 HOOK, N-terminal
Family IPR027719 Protein Daple
Homologous_superfamily IPR036872 CH domain superfamily
Domain Details Per Protein
Protein Length Calponin homology domain CH domain superfamily HOOK, N-terminal Protein Daple
UniProtKB:A0A2R8QCI3 2023
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations