Gene

pde5aa

ID
ZDB-GENE-100414-2
Name
phosphodiesterase 5A, cGMP-specific, a
Symbol
pde5aa Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have 3',5'-cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Li et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pde5aa Human Ortholog
No data available
Associated With pde5aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Family IPR023088 3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
Domain Details Per Protein
Protein Length 3'5'-cyclic nucleotide phosphodiesterase 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
UniProtKB:E7F690 922
UniProtKB:A0A0G2LA49
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations