Gene
pde5aa
- ID
- ZDB-GENE-100414-2
- Name
- phosphodiesterase 5A, cGMP-specific, a
- Symbol
- pde5aa Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have 3',5'-cyclic-nucleotide phosphodiesterase activity and metal ion binding activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Li et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023174 | 3'5'-cyclic nucleotide phosphodiesterase, conserved site |
| Domain | IPR002073 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
| Domain | IPR003018 | GAF domain |
| Domain | IPR003607 | HD/PDEase domain |
| Family | IPR023088 | 3'5'-cyclic nucleotide phosphodiesterase |
| Homologous_superfamily | IPR029016 | GAF-like domain superfamily |
| Homologous_superfamily | IPR036971 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | 3'5'-cyclic nucleotide phosphodiesterase | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | GAF domain | GAF-like domain superfamily | HD/PDEase domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F690
|
922 | |||||||
|
UniProtKB:A0A0G2LA49
|
||||||||
|
UniProtKB:A0A8M3AYL0
|
922 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance