ZFIN ID: ZDB-GENE-100408-5
Gene Name: G protein-coupled receptor kinase interacting ArfGAP 1
Gene Symbol: git1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity and metal ion binding activity. Involved in angiogenesis. Is expressed in head. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human GIT1 (GIT ArfGAP 1).
Genome Resources: Alliance (1),  Gene:568935 (1),  Ensembl(GRCz11):ENSDARG00000039489 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from Liu et al., 2012
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35903 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-git1 N/A 1
    MO2-git1 N/A 1
    DISEASE ASSOCIATED WITH git1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH git1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA git1-201 (1)    Ensembl 5031
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM git1 No data available
    MARKER RELATIONSHIPS
    git1 Contained in: [BAC] CH211-190A13 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005157670 (1)
    Genomic GenBank:CU570681 (1) 116371 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IPR8 (1) 761 aa
    Sequence Information (all 11)
    ORTHOLOGY for git1 ( Chr: 15 )
    CITATIONS (14)