Gene

kcnk18

ID
ZDB-GENE-100405-2
Name
potassium channel, subfamily K, member 18
Symbol
kcnk18 Nomenclature History
Previous Names
  • K2P18.1 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits outward rectifier potassium channel activity. Involved in stabilization of membrane potential. Predicted to localize to integral component of plasma membrane. Is expressed in brain and eye. Human ortholog(s) of this gene implicated in migraine with aura. Orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 3 from Rahm et al., 2014
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnk18 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Migraine, with or without aura, susceptibility to, 13} 613656
Associated With kcnk18 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013099 Potassium channel domain
Family IPR003092 Two pore domain potassium channel, TASK family
Family IPR003280 Two pore domain potassium channel
Domain Details Per Protein
Protein Length Potassium channel domain Two pore domain potassium channel Two pore domain potassium channel, TASK family
UniProtKB:F1QFD1 389
UniProtKB:R4R1T7 391
UniProtKB:D7NVC0 391
UniProtKB:A0A2R8QJP1 391
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations