Gene
kcnk18
- ID
- ZDB-GENE-100405-2
- Name
- potassium channel, subfamily K, member 18
- Symbol
- kcnk18 Nomenclature History
- Previous Names
-
- K2P18.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits outward rectifier potassium channel activity. Involved in stabilization of membrane potential. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in migraine with aura. Is expressed in brain and eye. Orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rahm et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Migraine, with or without aura, susceptibility to, 13} | 613656 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Potassium channel domain | Two pore domain potassium channel | Two pore domain potassium channel, TASK family |
|---|---|---|---|---|
|
UniProtKB:D7NVC0
|
391 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnk18-201
(1)
|
Ensembl | 1,241 nt |
Interactions and Pathways
No data available
Plasmids