Gene
nlgn4xb
- ID
- ZDB-GENE-100309-1
- Name
- neuroligin 4 X-linked b
- Symbol
- nlgn4xb Nomenclature History
- Previous Names
-
- nlgn4a (1)
- nlgn4b
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Is expressed in several structures, including brain; cranial ganglion; eye; gonad; and swim bladder. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Orthologous to human NLGN4X (neuroligin 4 X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QK81
|
795 | |||||
|
UniProtKB:D0EVX3
|
795 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlgn4xa-202
(1)
|
Ensembl | 2,532 nt | ||
| mRNA |
nlgn4xa-203
(1)
|
Ensembl | 4,719 nt | ||
| mRNA |
nlgn4xb-201
(1)
|
Ensembl | 2,900 nt | ||
| mRNA |
nlgn4xb-202
(1)
|
Ensembl | 2,679 nt | ||
| mRNA |
nlgn4xb-203
(1)
|
Ensembl | 2,880 nt |
Interactions and Pathways
No data available
Plasmids
No data available