Gene

mmp19

ID

ZDB-GENE-100308-3

Name

matrix metallopeptidase 19

Symbol

mmp19 Nomenclature History

Previous Names

zmp:0000001022 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular matrix. Orthologous to human MMP19 (matrix metallopeptidase 19).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mmp19 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cavitary optic disc anomalies	611543

Associated With mmp19 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018486	Hemopexin, conserved site
Domain	IPR000585	Hemopexin-like domain
Domain	IPR001818	Peptidase M10, metallopeptidase
Domain	IPR002477	Peptidoglycan binding-like
Domain	IPR006026	Peptidase, metallopeptidase
Domain	IPR033739	Peptidase M10A, catalytic domain
Family	IPR021190	Peptidase M10A
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036365	PGBD-like superfamily
Homologous_superfamily	IPR036375	Hemopexin-like domain superfamily
Repeat	IPR018487	Hemopexin-like repeats

Domain Details Per Protein

Protein	Additional Resources	Length	Hemopexin, conserved site	Hemopexin-like domain	Hemopexin-like domain superfamily	Hemopexin-like repeats	Metallopeptidase, catalytic domain superfamily	Peptidase M10A	Peptidase M10A, catalytic domain	Peptidase M10, metallopeptidase	Peptidase, metallopeptidase	Peptidoglycan binding-like	PGBD-like superfamily
UniProtKB:A0AB32TZ88	InterPro	478

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	mmp19-201 (1) Ensembl	Ensembl		1,631 nt	Select Tool ZFIN BLAST
mRNA	mmp19-202 (1) Ensembl	Ensembl		1,323 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations