Gene

atp8a2

ID
ZDB-GENE-100209-2
Name
ATPase phospholipid transporting 8A2
Symbol
atp8a2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in phospholipid translocation. Predicted to localize to plasma membrane and trans-Golgi network. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome. Orthologous to human ATP8A2 (ATPase phospholipid transporting 8A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp8a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cerebellar ataxia, mental retardation and dysequlibrium syndrome Alliance ?Cerebellar ataxia, mental retardation, and dysequilibrium syndrome 4 615268
Associated With atp8a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR032630 P-type ATPase, C-terminal
Domain IPR032631 P-type ATPase, N-terminal
Domain IPR044492 P-type ATPase, haloacid dehalogenase domain
Family IPR001757 P-type ATPase
Family IPR006539 P-type ATPase, subfamily IV
Homologous_superfamily IPR008250 P-type ATPase, A domain superfamily
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR023298 P-type ATPase, transmembrane domain superfamily
Homologous_superfamily IPR023299 P-type ATPase, cytoplasmic domain N
Homologous_superfamily IPR036412 HAD-like superfamily
PTM IPR018303 P-type ATPase, phosphorylation site
Domain Details Per Protein
Protein Length HAD-like superfamily HAD superfamily P-type ATPase P-type ATPase, A domain superfamily P-type ATPase, C-terminal P-type ATPase, cytoplasmic domain N P-type ATPase, haloacid dehalogenase domain P-type ATPase, N-terminal P-type ATPase, phosphorylation site P-type ATPase, subfamily IV P-type ATPase, transmembrane domain superfamily
UniProtKB:A0A2R8QNN7 1313
UniProtKB:K7DY26 186
UniProtKB:F1RDE6 1135
UniProtKB:A0A2R8QEZ8 1208
UniProtKB:X1WCP3 1211
UniProtKB:A0A2R8Q8E4 1205
UniProtKB:A0A2R8PW01 1208
UniProtKB:A0A286Y9U6 1198
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations