ZFIN ID: ZDB-GENE-100209-1
Gene Name: ring finger protein (C3H2C3 type) 6
Gene Symbol: rnf6    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in positive regulation of transcription, DNA-templated; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human RNF6 (ring finger protein 6).
Genome Resources: Alliance (1),  Gene:100359398 (1),  Ensembl(GRCz11):ENSDARG00000077955 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6766 Point Mutation Unknown Premature Stop ENU
sa15269 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rnf6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    esophageal cancer Alliance Esophageal carcinoma, somatic 133239
    DISEASE ASSOCIATED WITH rnf6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rnf6-201 (1)    Ensembl 4578
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnf6 No data available
    MARKER RELATIONSHIPS
    rnf6 Contained in: [BAC] CH211-202A8 (1)
    rnf6 Encodes: [EST] wz11866 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_017353871 (1)
    Genomic GenBank:AL929009 (1) 208279 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R4P2 (1) 734 aa
    Sequence Information (all 15)
    ORTHOLOGY for rnf6 ( Chr: 24 )
    CITATIONS (17)