Gene

pi4kaa

ID
ZDB-GENE-100204-2
Name
phosphatidylinositol 4-kinase, catalytic, alpha a
Symbol
pi4kaa Nomenclature History
Previous Names
  • pi4ka (1)
  • PI4KIII-alpha (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have 1-phosphatidylinositol 4-kinase activity. Involved in embryonic pectoral fin morphogenesis. Predicted to localize to cytoplasm and plasma membrane. Is expressed in brain; pectoral fin; pharyngeal arch; and somite. Orthologous to human PI4KA (phosphatidylinositol 4-kinase alpha).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 1 from Ma et al., 2009
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pi4kaa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis 616531
Associated With pi4kaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
Domain IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
Domain IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
Family IPR015433 Phosphatidylinositol kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036940 Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
Homologous_superfamily IPR042236 Phosphoinositide 3-kinase, accessory (PIK) domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold Phosphatidylinositol 3-/4-kinase, catalytic domain Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily Phosphatidylinositol 3/4-kinase, conserved site Phosphatidylinositol kinase Phosphoinositide 3-kinase, accessory (PIK) domain Phosphoinositide 3-kinase, accessory (PIK) domain superfamily Protein kinase-like domain superfamily
UniProtKB:Q49GP4 2059
UniProtKB:F1RCP0 2059
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations