ZFIN ID: ZDB-GENE-100112-1
Gene Name: NADH:ubiquinone oxidoreductase complex assembly factor 6
Gene Symbol: ndufaf6    Nomenclature History

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Previous Names: gb:bc097249 (1), si:ch211-233e16.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFAF6 (NADH:ubiquinone oxidoreductase complex assembly factor 6).
Genome Resources: Alliance (1),  Gene:569692 (1),  Ensembl(GRCz11):ENSDARG00000053652 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Lam et al., 2011
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17886 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28721 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    TALEN1-ndufaf6
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ndufaf6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Mitochondrial complex I deficiency, nuclear type 17 618239
    DISEASE ASSOCIATED WITH ndufaf6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial respiratory chain complex I assembly (more)
    Cellular Component mitochondrion (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Homologous_superfamily IPR008949 Isoprenoid synthase domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ndufaf6-201 (1)    Ensembl 1108
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ndufaf6 No data available
    MARKER RELATIONSHIPS
    ndufaf6 Contained in: [BAC] CH211-233E16 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_021466778 (1)
    Genomic GenBank:BX294187 (1) 117562 nt
    Select Tool
    Polypeptide UniProtKB:Q4V8Q6 (1) 344 aa
    Sequence Information (all 9)
    ORTHOLOGY for ndufaf6 ( Chr: 16 )
    CITATIONS (18)