ZFIN ID: ZDB-GENE-100107-1
Gene Name: growth differentiation factor 2
Gene Symbol: gdf2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: bmp9 (2)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have cytokine activity. Involved in angiogenesis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia. Orthologous to human GDF2 (growth differentiation factor 2).
Genome Resources: Alliance (1),  Gene:563287 (1),  Ensembl(GRCz11):ENSDARG00000059173 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21995 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-gdf2 N/A 2
    MO2-gdf2 N/A 1
    DISEASE ASSOCIATED WITH gdf2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    hereditary hemorrhagic telangiectasia Alliance Telangiectasia, hereditary hemorrhagic, type 5 615506
    DISEASE ASSOCIATED WITH gdf2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component extracellular region (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gdf2-201 (1)    Ensembl 1170
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM gdf2 No data available
    MARKER RELATIONSHIPS
    gdf2 Contained in: [BAC] CH211-77E10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001171586 (1)
    Genomic GenBank:CR450691 (1) 157371 nt
    Select Tool
    Polypeptide UniProtKB:F1QWZ4 (1) 389 aa
    Sequence Information (all 7)
    ORTHOLOGY for gdf2 ( Chr: 12 )
    CITATIONS (20)