ZFIN ID: ZDB-GENE-091211-1
Gene Name: cytochrome P450, family 2, subfamily k, polypeptide 19
Gene Symbol: cyp2k19    Nomenclature History

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Previous Name: zgc:198195

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Is expressed in intestine and liver. Orthologous to human CYP2W1 (cytochrome P450 family 2 subfamily W member 1).
Genome Resources: Alliance (1),  Gene:562304 (1),  Ensembl(GRCz11):ENSDARG00000101861 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Cheng et al., 2006
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp2k19 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cyp2k19 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component cytoplasm (more)
Molecular Function heme binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Conserved_site IPR017972 Cytochrome P450, conserved site
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cyp2k19-201 (1)    Ensembl 3437
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cyp2k19 No data available
MARKER RELATIONSHIPS
cyp2k19 Contained in: [BAC] CH211-155I15 (1)
cyp2k19 Encodes: [EST] wz1197
[cDNA] MGC:198191 (1), MGC:198195 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001079704 (1) 1721 bp
Genomic GenBank:AL929078 (1) 171571 bp
Select Tool
Polypeptide UniProtKB:A0PGM0 (1) 502 aa
Sequence Information (all 28)
ORTHOLOGY for cyp2k19 ( Chr: 3 )
CITATIONS (22)