ZFIN ID: ZDB-GENE-091207-3
Gene Name: tribbles pseudokinase 2
Gene Symbol: trib2    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have mitogen-activated protein kinase kinase binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of MAP kinase activity. Predicted to localize to the nucleus. Orthologous to human TRIB2 (tribbles pseudokinase 2).
Genome Resources: Alliance (1),  Gene:100331041 (1),  Ensembl(GRCz11):ENSDARG00000068179 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16440 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23798 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH trib2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH trib2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000719 Protein kinase domain
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    Family IPR024104 Pseudokinase tribbles family/serine-threonine-protein kinase 40
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM trib2 No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002667743 (1) 3118 bp
    Genomic GenBank:CABZ01063106 (1) 9101 bp
    Polypeptide UniProtKB:E7F3S2 (1) 207 aa
    Sequence Information (all 6)
    ORTHOLOGY for trib2 ( Chr: 20 )
    CITATIONS (16)