ZFIN ID: ZDB-GENE-091204-5
Gene Name: nicotinamide nucleotide transhydrogenase 2
Gene Symbol: nnt2    Nomenclature History

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Previous Name: si:ch1073-139a18.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have NAD binding activity; NAD(P)+ transhydrogenase activity; and NADP binding activity. Predicted to be involved in NADPH regeneration. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Orthologous to human NNT (nicotinamide nucleotide transhydrogenase).
Genome Resources: Alliance (1),  Gene:108179934 (1),  Ensembl(GRCz11):ENSDARG00000092522 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-nnt2 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nnt2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Glucocorticoid deficiency 4, with or without mineralocorticoid deficiency 614736
DISEASE ASSOCIATED WITH nnt2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component integral component of membrane (more)
Molecular Function NAD(P)+ transhydrogenase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA nnt2-201 (1)    Ensembl 2528
nnt2-202 (1)    Ensembl 220
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nnt2 No data available
MARKER RELATIONSHIPS
nnt2 Contained in: [Fosmid] CH1073-139A18 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_017351991 (1)
Genomic GenBank:CU929075 (1) 17936 nt
Polypeptide UniProtKB:E9QDE7 (1) 802 aa
Sequence Information (all 10)
ORTHOLOGY for nnt2 ( Chr: 18 )
CITATIONS (14)