Gene
mhc2d8.37a1
- ID
- ZDB-GENE-091204-401
- Name
- major histocompatibility complex class II d8.37a1
- Symbol
- mhc2d8.37a1 Nomenclature History
- Previous Names
-
- si:zfos-367g9.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in antigen processing and presentation and immune response. Predicted to localize to MHC class II protein complex and integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); glucose metabolism disease (multiple); hematologic cancer (multiple); and liver disease (multiple). Orthologous to human HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR001003 | MHC class II, alpha chain, N-terminal |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014745 | MHC class II, alpha/beta chain, N-terminal |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | MHC classes I/II-like antigen recognition protein | MHC class II, alpha/beta chain, N-terminal | MHC class II, alpha chain, N-terminal |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QNN0
|
236 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
si:zfos-367g9.1-201
(1)
|
Havana | 939 nt |
Interactions and Pathways
No data available
Plasmids
No data available