Gene

cpa6

ID
ZDB-GENE-091204-331
Name
carboxypeptidase A6
Symbol
cpa6 Nomenclature History
Previous Names
  • si:dkey-78n18.1 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Enables carboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including head; pectoral fin; pectoral fin bud; segmental plate; and tail bud. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Lopes et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cpa6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial febrile seizures 11 Alliance Febrile seizures, familial, 11 614418
familial temporal lobe epilepsy 5 Alliance Epilepsy, familial temporal lobe, 5 614417
Associated With cpa6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000834 Peptidase M14, carboxypeptidase A
Domain IPR003146 Carboxypeptidase, activation peptide
Homologous_superfamily IPR036990 Metallocarboxypeptidase-like, propeptide
Domain Details Per Protein
Protein Length Carboxypeptidase, activation peptide Metallocarboxypeptidase-like, propeptide Peptidase M14, carboxypeptidase A
UniProtKB:A0A2R8QFE3 408
UniProtKB:E7F2H8 442
UniProtKB:E9QHZ1 175
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations