ZFIN ID: ZDB-GENE-091204-190
Gene Name: si:dkey-6b12.5
Gene Symbol: si:dkey-6b12.5    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; actin filament organization; and regulation of cell shape. Predicted to localize to the cell cortex; cell projection; and plasma membrane. Orthologous to human RHOBTB3 (Rho related BTB domain containing 3).
Genome Resources: Alliance (1),  Gene:562804 (1),  Ensembl(GRCz11):ENSDARG00000090036 (1)

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37249 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH si:dkey-6b12.5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH si:dkey-6b12.5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process vesicle-mediated transport (more)
    Cellular Component cell cortex (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000210 BTB/POZ domain
    Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
    Family IPR031260 Rho-related BTB domain-containing protein 3
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:dkey-6b12.5-201 (1)    Ensembl 2278
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM si:dkey-6b12.5 No data available
    MARKER RELATIONSHIPS
    si:dkey-6b12.5 Contained in: [BAC] DKEY-6B12 (1) (order this), DKEY-89G21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_686178 (1)
    Genomic GenBank:BX511081 (1) 210246 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7EYA0 (1) 619 aa
    Sequence Information (all 7)
    ORTHOLOGY for si:dkey-6b12.5 ( Chr: 21 )
    CITATIONS (11)