Gene
ppip5k2
- ID
- ZDB-GENE-091204-125
- Name
- diphosphoinositol pentakisphosphate kinase 2
- Symbol
- ppip5k2 Nomenclature History
- Previous Names
-
- im:7137778
- si:dkey-117i20.1
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable 5-diphosphoinositol pentakisphosphate 1-kinase activity and inositol hexakisphosphate kinase activity. Predicted to be involved in inositol metabolic process and inositol phosphate biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 100. Orthologous to human PPIP5K2 (diphosphoinositol pentakisphosphate kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137778 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 100 | Alliance | Deafness, autosomal recessive 100 | 618422 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033379 | Histidine acid phosphatase active site |
| Domain | IPR040557 | VIP1, N-terminal |
| Family | IPR000560 | Histidine phosphatase superfamily, clade-2 |
| Family | IPR037446 | Histidine acid phosphatase, VIP1 family |
| Homologous_superfamily | IPR029033 | Histidine phosphatase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Histidine acid phosphatase active site | Histidine acid phosphatase, VIP1 family | Histidine phosphatase superfamily | Histidine phosphatase superfamily, clade-2 | VIP1, N-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AWJ0 | InterPro | 1184 | |||||
| UniProtKB:A0A8M3AWH6 | InterPro | 1289 | |||||
| UniProtKB:A0A8M2B378 | InterPro | 1242 | |||||
| UniProtKB:A0A8M9QKU2 | InterPro | 1266 | |||||
| UniProtKB:A0A8M9QGS3 | InterPro | 1226 | |||||
| UniProtKB:A0A8M3B611 | InterPro | 1270 | |||||
| UniProtKB:A0A8M3B330 | InterPro | 1252 | |||||
| UniProtKB:A0A8M2B2S9 | InterPro | 1303 | |||||
| UniProtKB:A0A8M3BCT9 | InterPro | 1310 | |||||
| UniProtKB:A0A8M1RHG9 | InterPro | 1282 | |||||
| UniProtKB:A0A8M2B3C4 | InterPro | 1263 | |||||
| UniProtKB:A0AB32U2I9 | InterPro | 1212 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
ppip5k2-205
(1)
|
Ensembl | 795 nt | ||
| mRNA |
ppip5k2-201
(1)
|
Ensembl | 3,912 nt | ||
| mRNA |
ppip5k2-206
(1)
|
Ensembl | 5,059 nt | ||
| ncRNA |
ppip5k2-002
(1)
|
Ensembl | 327 nt | ||
| ncRNA |
ppip5k2-003
(1)
|
Ensembl | 429 nt | ||
| ncRNA |
ppip5k2-005
(1)
|
Ensembl | 530 nt |
Interactions and Pathways
No data available
Plasmids
No data available