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ZIRC
ZFIN ID: ZDB-GENE-091118-71
Gene Name: POU class 6 homeobox 2
Gene Symbol: pou6f2    Nomenclature History

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Previous Name: si:ch211-124o16.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in regeneration. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human POU6F2 (POU class 6 homeobox 2).
Genome Resources: Alliance (1),  Gene:100001518 (1),  Ensembl(GRCz11):ENSDARG00000086362 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Powell et al., 2014
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10016 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pou6f2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pou6f2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Wilms tumor susceptibility-5} 601583
    DISEASE ASSOCIATED WITH pou6f2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regeneration (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pou6f2-203 (1)    Ensembl 4198
    ncRNA pou6f2-002 (1) 570
    pou6f2-003 (1) 809
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pou6f2 No data available
    MARKER RELATIONSHIPS
    pou6f2 Contained in: [BAC] CH211-124O16 (1) (order this), CH211-146L10 (1) (order this), DKEY-123G19 (1) (order this), DKEY-253J12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017353999 (1)
    Genomic GenBank:CR391965 (1) 183705 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4J6S2 (1) 694 aa
    Sequence Information (all 12)
    ORTHOLOGY for pou6f2 ( Chr: 24 )
    CITATIONS (15)