ZFIN ID: ZDB-GENE-091118-52
Gene Name: heme oxygenase 2b
Gene Symbol: hmox2b    Nomenclature History

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Previous Name: si:dkey-254e1.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have heme binding activity and heme oxygenase (decyclizing) activity. Predicted to be involved in iron ion homeostasis; porphyrin-containing compound catabolic process; and response to oxidative stress. Predicted to localize to integral component of membrane. Is expressed in brain; gill; and liver. Orthologous to human HMOX2 (heme oxygenase 2).
Genome Resources: Alliance (1),  Gene:100329531 (1),  Ensembl(GRCz11):ENSDARG00000078452 (1)
GENE EXPRESSION
All Expression Data: 6 figures from Holowiecki et al., 2016
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10015 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hmox2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hmox2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heme oxidation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function heme oxygenase (decyclizing) activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hmox2b-202 (1)    Ensembl 1103
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hmox2b No data available
    MARKER RELATIONSHIPS
    hmox2b Contained in: [BAC] DKEY-254E1 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_002661099 (1)
    Genomic GenBank:CT573469 (1) 156477 nt
    Select Tool
    Polypeptide UniProtKB:E7F079 (1) 318 aa
    Sequence Information (all 15)
    ORTHOLOGY for hmox2b ( Chr: 3 )
    CITATIONS (19)