ZFIN ID: ZDB-GENE-091118-25
Gene Name: AP2 associated kinase 1b
Gene Symbol: aak1b    Nomenclature History

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Previous Names: aak1, si:dkey-261l11.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway; protein phosphorylation; and regulation of clathrin-dependent endocytosis. Predicted to localize to cytoplasm. Orthologous to human AAK1 (AP2 associated kinase 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000077686 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21810 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27677 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aak1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aak1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aak1b-202 (1)    Ensembl 1451
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aak1b No data available
    MARKER RELATIONSHIPS
    aak1b Contained in: [BAC] CH211-271B8 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:BX005297 (1) 156906 nt
    Select Tool
    Polypeptide UniProtKB:E7F2L1 (1) 1055 aa
    Sequence Information (all 3)
    ORTHOLOGY for aak1b ( Chr: 10 )
    CITATIONS (12)