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ZIRC
ZFIN ID: ZDB-GENE-091118-124
Gene Name: RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Gene Symbol: rasgrp2    Nomenclature History

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Previous Name: si:ch211-247j24.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 18. Orthologous to human RASGRP2 (RAS guanyl releasing protein 2).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000062328 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3110 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH rasgrp2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
platelet-type bleeding disorder 18 Alliance ?Bleeding disorder, platelet-type, 18 615888
DISEASE ASSOCIATED WITH rasgrp2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular signal transduction (more)
Molecular Function calcium ion binding (more)
GO Terms (all 5)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rasgrp2-202 (1)    Ensembl 1642
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rasgrp2 No data available
MARKER RELATIONSHIPS
rasgrp2 Contained in: [BAC] CH211-247J24 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
Genomic GenBank:CR376834 (1) 150120 bp
Select Tool
Polypeptide UniProtKB:F1R763 (1) 579 aa
Sequence Information (all 3)
ORTHOLOGY for rasgrp2 ( Chr: 21 )
CITATIONS (13)