ZFIN is now using GRCz12tu for Genomic Data
Gene
osbpl2a
- ID
- ZDB-GENE-091116-46
- Name
- oxysterol binding protein-like 2a
- Symbol
- osbpl2a Nomenclature History
- Previous Names
-
- si:ch211-89o10.1
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cholesterol binding activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Is expressed in ventricular zone. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67 and dyschromatosis, ichthyosis, deafness, and atopic disease. Orthologous to human OSBPL2 (oxysterol binding protein like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 67 | Alliance | Deafness, autosomal dominant 67 | 616340 |
| dyschromatosis, ichthyosis, deafness, and atopic disease | Alliance | Dyschromatosis, ichthyosis, deafness, and atopic disease | 621400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Oxysterol-binding protein | Oxysterol-binding protein, conserved site | Oxysterol-binding protein superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3AVL0 | InterPro | 322 | |||
| UniProtKB:E7F4S3 | InterPro | 467 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
osbpl2a-201
(1)
|
Ensembl | 1,543 nt | ||
| mRNA |
osbpl2a-202
(1)
|
Ensembl | 1,428 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers