ZFIN Gene: capn5b

ZFIN ID: ZDB-GENE-091116-29

ZFIN ID: ZDB-GENE-091116-29

Gene Name:

calpain 5b

Gene Symbol:

capn5b

Sequence Ontology ID :

SO:0000704

Previous Name:

si:dkey-163i6.4

Location:

Chr: 21 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to the cytoplasm. Orthologous to human CAPN5 (calpain 5).

GENE EXPRESSION
All Expression Data:	6 figures from Coomer et al., 2018
Wild-type Stages, Structures:	Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
	cerebellum diencephalon floor plate hindbrain midbrain optic tectum retina retinal cone cell photoreceptor inner segment retinal outer nuclear layer whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la014017Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la021880Tg	Transgenic Insertion	Unknown	Unknown	DNA
la028322Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa44967	Point Mutation	Unknown	Unknown	ENU

Targeting reagents:

MO1-capn5b (1)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH capn5b HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
	Vitreoretinopathy, neovascular inflammatory	193235

DISEASE ASSOCIATED WITH capn5b VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	proteolysis (more)
Cellular Component	cytoplasm (more)
Molecular Function	calcium-dependent cysteine-type endopeptidase activity (more)

GO Terms (all 6)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000008 (1) InterPro:IPR000169 (1) InterPro:IPR001300 (1) InterPro:IPR022682 (1) InterPro:IPR022683 (1) InterPro:IPR022684 (1) InterPro:IPR033883 (1) InterPro:IPR033884 (1) InterPro:IPR035892 (1) InterPro:IPR036213 (1) InterPro:IPR038765 (1)	PROSITE:PS00139 (1) PROSITE:PS50004 (1) PROSITE:PS50203 (1)	Pfam:PF00168 (1) Pfam:PF00648 (1) Pfam:PF01067 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	capn5b-201 (1)	1943	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM capn5b No data available

MARKER RELATIONSHIPS

capn5bContained in:

[BAC] DKEY-163I6 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_001345078 (1)	2571bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	RefSeq:NW_018395349 (1)		Blast at MegaBLAST
Polypeptide	UniProtKB:E7F7F1 (1)	642aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 13)

OTHER capn5b GENE PAGES

Alliance (1)

Gene:100006332 (1)

VEGA:OTTDARG00000031544 (1)

Ensembl(GRCz11):ENSDARG00000069748 (1)

ORTHOLOGY for capn5b (Chr: 21)

CITATIONS (22)

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