Gene

capn5b

ID
ZDB-GENE-091116-29
Name
calpain 5b
Symbol
capn5b Nomenclature History
Previous Names
  • si:dkey-163i6.4
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Is predicted to enable calcium-dependent cysteine-type endopeptidase activity. Involved in proteolysis. Is expressed in nervous system. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Orthologous to human CAPN5 (calpain 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With capn5b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neovascular inflammatory vitreoretinopathy Alliance Vitreoretinopathy, neovascular inflammatory 193235
Associated With capn5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Domain IPR000008 C2 domain
Domain IPR001300 Peptidase C2, calpain, catalytic domain
Domain IPR022682 Peptidase C2, calpain, large subunit, domain III
Domain IPR022683 Peptidase C2, calpain, domain III
Domain IPR033883 Calpain subdomain III
Domain IPR033884 Calpain C2 domain
Family IPR022684 Peptidase C2, calpain family
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR036213 Calpain large subunit, domain III superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily Calpain C2 domain Calpain large subunit, domain III superfamily Calpain subdomain III Cysteine peptidase, cysteine active site Papain-like cysteine peptidase superfamily Peptidase C2, calpain, catalytic domain Peptidase C2, calpain, domain III Peptidase C2, calpain family Peptidase C2, calpain, large subunit, domain III
UniProtKB:E7F7F1 642
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations