Gene

smarcad1b

ID
ZDB-GENE-091113-61
Name
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
Symbol
smarcad1b Nomenclature History
Previous Names
  • si:dkey-76p7.6
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA binding activity; DNA-dependent ATPase activity; and chromatin binding activity. Predicted to be involved in ATP-dependent chromatin remodeling and DNA double-strand break processing. Predicted to localize to nucleus and site of double-strand break. Human ortholog(s) of this gene implicated in BASAN syndrome and adermatoglyphia. Orthologous to human SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smarcad1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
adermatoglyphia Alliance Adermatoglyphia 136000
BASAN syndrome Alliance Basan syndrome 129200
Huriez syndrome 181600
Associated With smarcad1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000330 SNF2-related domain
Domain IPR001650 Helicase, C-terminal
Domain IPR003892 Ubiquitin system component CUE
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Homologous_superfamily IPR009060 UBA-like superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase SNF2-like, N-terminal domain superfamily SNF2-related domain UBA-like superfamily Ubiquitin system component CUE
UniProtKB:E7F1C4 954
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations