ZFIN Gene: ank1b

ZFIN ID: ZDB-GENE-091113-6

ZFIN ID: ZDB-GENE-091113-6

Gene Name:

ankyrin 1, erythrocytic b

Gene Symbol:

ank1b Nomenclature History

Previous Name:

si:ch211-263m18.3 (1)

Gene Type:

protein_coding_gene

Location:

Chr: 21 Mapping Details/Browsers

Description:

Predicted to have cytoskeletal anchor activity; ion channel binding activity; and spectrin binding activity. Predicted to be involved in protein localization to plasma membrane. Predicted to localize to neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).

Genome Resources:

Alliance (1), Gene:797662 (1), Ensembl(GRCz11):ENSDARG00000074777 (2)

GENE EXPRESSION No data available

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa917	Point Mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa12882	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa15660	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa18669	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37286	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37287	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this)
sa37288	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
MO1-ank1b	N/A	1

PHENOTYPE No data available

DISEASE ASSOCIATED WITH ank1b HUMAN ORTHOLOG

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spherocytosis type 1	Alliance	Spherocytosis, type 1	182900

DISEASE ASSOCIATED WITH ank1b VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	signal transduction (more)
Cellular Component	neuron projection (more)
Molecular Function	cytoskeletal anchor activity (more)

GO Terms (all 7)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	ank1b-204 (1)	5534	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ank1b-003 (1)	746	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	ank1b-004 (1)	695	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM ank1b No data available

MARKER RELATIONSHIPS

ank1b Contained in:

[BAC] CH211-174L22 (1), CH211-263M18 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_021469065 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:AL773542 (1)	163443 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A2R8RQY1 (1)	1767 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 23)

ORTHOLOGY for ank1b ( Chr: 21 )

CITATIONS (17)

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