Gene
ank1b
- ID
- ZDB-GENE-091113-6
- Name
- ankyrin 1, erythrocytic b
- Symbol
- ank1b Nomenclature History
- Previous Names
-
- si:ch211-263m18.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within signal transduction. Predicted to be located in several cellular components, including cell periphery; sarcoplasmic reticulum; and spectrin-associated cytoskeleton. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spherocytosis type 1 | Alliance | Spherocytosis, type 1 | 182900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000488 | Death domain |
| Domain | IPR000906 | ZU5 domain |
| Domain | IPR040745 | Ankyrin, UPA domain |
| Family | IPR051165 | Multifunctional Ankyrin Repeat Domain-Containing Protein |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ankyrin, UPA domain | Death domain | Death-like domain superfamily | Multifunctional Ankyrin Repeat Domain-Containing Protein | ZU5 domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PIW2 | InterPro | 1930 | |||||||
| UniProtKB:A0A8M9PD85 | InterPro | 1956 | |||||||
| UniProtKB:A0A8M9PR23 | InterPro | 1963 | |||||||
| UniProtKB:A0A8M9PUL5 | InterPro | 1919 | |||||||
| UniProtKB:A0A8M9PR28 | InterPro | 1769 | |||||||
| UniProtKB:A0A8M9PDB9 | InterPro | 2091 | |||||||
| UniProtKB:A0AB32TI65 | InterPro | 2074 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ank1b-201
(1)
|
Ensembl | 5,211 nt | ||
| mRNA |
ank1b-204
(1)
|
Ensembl | 5,534 nt | ||
| mRNA |
ank1b-205
(1)
|
Ensembl | 5,304 nt | ||
| mRNA |
ank1b-206
(1)
|
Ensembl | 4,527 nt | ||
| mRNA |
ank1b-207
(1)
|
Ensembl | 3,999 nt | ||
| mRNA |
ank1b-208
(1)
|
Ensembl | 5,157 nt | ||
| ncRNA |
ank1b-003
(1)
|
Ensembl | 746 nt | ||
| ncRNA |
ank1b-004
(1)
|
Ensembl | 695 nt |
Interactions and Pathways
No data available
Plasmids
No data available