Gene

ank1b

ID

ZDB-GENE-091113-6

Name

ankyrin 1, erythrocytic b

Symbol

ank1b Nomenclature History

Previous Names

si:ch211-263m18.3 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have cytoskeletal anchor activity; ion channel binding activity; and spectrin binding activity. Predicted to be involved in protein localization to plasma membrane. Predicted to localize to neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).

Genome Resources

Note

None

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

No data available

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ank1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spherocytosis type 1	Alliance	Spherocytosis, type 1	182900

Associated With ank1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Domain	IPR020683	Ankyrin repeat-containing domain
Domain	IPR040745	Ankyrin, UPA domain
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain	Ankyrin repeat-containing domain superfamily	Ankyrin, UPA domain	Death domain	Death-like domain superfamily	ZU5 domain
UniProtKB:A0A2R8Q894 InterPro	1294
UniProtKB:E7F0U4 InterPro	1736
UniProtKB:A0A2R8PYS3 InterPro	1167
UniProtKB:A0A2R8QT49 InterPro	1718
UniProtKB:A0A2R8RQY1 InterPro	1767
UniProtKB:F1QV17 InterPro	1703

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	ank1b-204 (1) Ensembl	5534 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ank1b-003 (1) Ensembl	746 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ank1b-004 (1) Ensembl	695 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Gene Tree: Ensembl

Citations