Gene
ank1b
- ID
- ZDB-GENE-091113-6
- Name
- ankyrin 1, erythrocytic b
- Symbol
- ank1b Nomenclature History
- Previous Names
-
- si:ch211-263m18.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cytoskeletal anchor activity; ion channel binding activity; and spectrin binding activity. Predicted to be involved in protein localization to plasma membrane. Predicted to localize to neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hereditary spherocytosis type 1 | Alliance | Spherocytosis, type 1 | 182900 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000488 | Death domain |
Domain | IPR000906 | ZU5 domain |
Domain | IPR020683 | Ankyrin repeat-containing domain |
Domain | IPR040745 | Ankyrin, UPA domain |
Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain | Ankyrin repeat-containing domain superfamily | Ankyrin, UPA domain | Death domain | Death-like domain superfamily | ZU5 domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A2R8Q894
|
1294 | |||||||
UniProtKB:E7F0U4
|
1736 | |||||||
UniProtKB:A0A2R8PYS3
|
1167 | |||||||
UniProtKB:A0A2R8QT49
|
1718 | |||||||
UniProtKB:A0A2R8RQY1
|
1767 | |||||||
UniProtKB:F1QV17
|
1703 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl