Gene

si:dkey-84o3.2

ID
ZDB-GENE-091113-19
Name
si:dkey-84o3.2
Symbol
si:dkey-84o3.2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:dkey-84o3.2 Human Ortholog
No data available
Associated With si:dkey-84o3.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR041489 PDZ domain 6
Family IPR001940 Peptidase S1C
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length PDZ domain PDZ domain 6 PDZ superfamily Peptidase S1C Peptidase S1, PA clan
UniProtKB:E9QFX7 209
UniProtKB:E7F3J5 113
UniProtKB:A0A0N4SUC1 137
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations