Gene
tnnt2b
- ID
- ZDB-GENE-091106-2
- Name
- troponin T type 2b (cardiac)
- Symbol
- tnnt2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have tropomyosin binding activity; troponin C binding activity; and troponin I binding activity. Predicted to be involved in cardiac muscle contraction and sarcomere organization. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1D | Alliance | Cardiomyopathy, dilated, 1D | 601494 |
| dilated cardiomyopathy 1D | Alliance | Left ventricular noncompaction 6 | 601494 |
| hypertrophic cardiomyopathy 2 | Alliance | Cardiomyopathy, hypertrophic, 2 | 115195 |
| restrictive cardiomyopathy 3 | Alliance | Cardiomyopathy, familial restrictive, 3 | 612422 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Troponin | Troponin domain superfamily | Troponin T |
|---|---|---|---|---|
|
UniProtKB:A0A8M6YZU8
|
242 | |||
|
UniProtKB:A0A8M6Z708
|
243 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnnt2b-201
(1)
|
Ensembl | 1,162 nt |
Interactions and Pathways
No data available
Plasmids
No data available