ZFIN ID: ZDB-GENE-091027-1
Gene Name: transforming growth factor, beta receptor 1 b
Gene Symbol: tgfbr1b
Sequence Ontology ID : SO:0000704

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Previous Name: alk5b (1)

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including SMAD binding activity, activin binding activity, and growth factor binding activity; predicted to be involved in activin receptor signaling pathway,  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tgfbr1b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Loeys-Dietz syndrome 1 Loeys-Dietz syndrome 1 609192
{Multiple self-healing squamous epithelioma, susceptibility to} 132800
{Multiple self-healing squamous epithelioma, susceptibility to} 132800
DISEASE ASSOCIATED WITH tgfbr1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000333 (1)
  • InterPro:IPR000472 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR003605 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS51256 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF01064 (1)
  • Pfam:PF08515 (1)
  • EC:2.7.11.30 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tgfbr1b-201 (1) 1918
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfbr1b No data available
    MARKER RELATIONSHIPS
    tgfbr1bContained in: [Fosmid] CH1073-59L16 (1) (order this), CH1073-209H20 (1) (order this), CH1073-293G9 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001115059 (1) 1917bp
    Genomic GenBank:FP016176 (1) 38091bp
    Select Tool
    Polypeptide UniProtKB:B0EXP7 (1) 505aa
    Sequence Clusters UniGene:120512 (1)
    Sequence Information (all 13)
    OTHER tgfbr1b GENE PAGES
  • Alliance (1)
  • Gene:792928 (1)
  • VEGA:OTTDARG00000034806 (1)
  • Ensembl(GRCz11):ENSDARG00000042259 (2)
  • ORTHOLOGY for tgfbr1b (Chr: 24)
    CITATIONS (24)