ZFIN ID: ZDB-GENE-091020-5
Gene Name: chimerin 2
Gene Symbol: chn2    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity. Predicted to be involved in regulation of GTPase activity. Orthologous to human CHN2 (chimerin 2).
Genome Resources: Alliance (1),  Gene:570999 (1),  Ensembl(GRCz11):ENSDARG00000011845 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22813 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22814 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chn2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chn2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000198 Rho GTPase-activating protein domain
    Domain IPR000980 SH2 domain
    Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
    Homologous_superfamily IPR008936 Rho GTPase activation protein
    Family IPR017356 Chimaerin
    Domain IPR020454 Diacylglycerol/phorbol-ester binding
    Domain IPR035840 Chimaerin, SH2 domain
    Homologous_superfamily IPR036860 SH2 domain superfamily
    Domain IPR037860 Chimaerin, RhoGAP domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chn2-202 (1)    Ensembl 1352
    ncRNA chn2-002 (1)    Ensembl 611
    chn2-003 (1)    Ensembl 701
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chn2 No data available
    MARKER RELATIONSHIPS
    chn2 Contained in: [BAC] CH73-362G18 (1), CH211-206N14, DKEYP-86H10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_694550 (1)
    Genomic GenBank:BX890611 (1) 181642 bp
    Select Tool
    Polypeptide UniProtKB:E7F3K5 (1) 466 aa
    Sequence Information (all 11)
    ORTHOLOGY for chn2 ( Chr: 16 )
    CITATIONS (15)