Gene

arap3

ID
ZDB-GENE-091019-1
Name
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Symbol
arap3 Nomenclature History
Previous Names
  • arfgap1 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable GTPase activator activity; metal ion binding activity; and phosphatidylinositol-3,4,5-trisphosphate binding activity. Acts upstream of or within lymphangiogenesis. Predicted to be located in cytoplasm. Is expressed in cardiovascular system; neurons; and somite. Orthologous to human ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Kartopawiro et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arap3 Human Ortholog
No data available
Associated With arap3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000159 Ras-associating (RA) domain
Domain IPR000198 Rho GTPase-activating protein domain
Domain IPR001164 Arf GTPase activating protein
Domain IPR001660 Sterile alpha motif domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR037858 ARAP, RhoGAP domain
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR037278 ARFGAP/RecO-like zinc finger
Homologous_superfamily IPR038508 ArfGAP domain superfamily
Domain Details Per Protein
Protein Length ARAP, RhoGAP domain ArfGAP domain superfamily ARFGAP/RecO-like zinc finger Arf GTPase activating protein PH-like domain superfamily Pleckstrin homology domain Ras-associating (RA) domain Rho GTPase-activating protein domain Rho GTPase activation protein Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily Ubiquitin-like domain superfamily
UniProtKB:A0A140LH27 1664
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations