ZFIN ID: ZDB-GENE-091019-1
Gene Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Gene Symbol: arap3    Nomenclature History

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Previous Name: arfgap1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity; metal ion binding activity; and phosphatidylinositol-3,4,5-trisphosphate binding activity. Involved in lymphangiogenesis. Is expressed in cardiovascular system; neurons; and somite. Orthologous to human ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3).
Genome Resources: Alliance (1),  Gene:558931 (1),  Ensembl(GRCz11):ENSDARG00000076801 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12354 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16286 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35696 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35697 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arap3 N/A 1
    MO2-arap3 N/A 1
    MO3-arap3 N/A 1
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH arap3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arap3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lymphangiogenesis (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arap3-201 (1)    Ensembl 8267
    ncRNA arap3-002 (1)    Ensembl 753
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arap3 No data available
    MARKER RELATIONSHIPS
    arap3 Contained in: [BAC] DKEY-91L18 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005173181 (1) 7072 nt
    Genomic GenBank:BX510930 (1) 95848 nt
    Select Tool
    Polypeptide UniProtKB:A0A140LH27 (1) 1664 aa
    Sequence Information (all 9)
    ORTHOLOGY for arap3 ( Chr: 14 )
    CITATIONS (16)