ZFIN ID: ZDB-GENE-091013-5
Gene Name: TEA domain family member 1b
Gene Symbol: tead1b    Nomenclature History

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Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II transcription factor binding activity. Predicted to be involved in hippo signaling and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to several human genes including TEAD1 (TEA domain transcription factor 1).
Genome Resources: Alliance (1),  Gene:100006454 (1),  Ensembl(GRCz11):ENSDARG00000059483 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026244Tg Transgenic Insertion Unknown Unknown DNA
sa41070 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tead1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sveinsson chorioretinal atrophy Alliance Sveinsson chorioretinal atrophy 108985
    DISEASE ASSOCIATED WITH tead1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hippo signaling (more)
    Cellular Component integral component of membrane (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000818 TEA/ATTS domain
    Domain IPR041086 YAP binding domain
    Family IPR016361 Transcriptional enhancer factor, metazoa
    Homologous_superfamily IPR038096 TEA/ATTS domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tead1b-202 (1)    Ensembl 9066
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tead1b No data available
    MARKER RELATIONSHIPS
    tead1b Contained in: [BAC] DKEY-288C23 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009303581 (1)
    Genomic GenBank:CT573494 (1) 132080 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QPG4 (1) 410 aa
    Sequence Information (all 38)
    ORTHOLOGY for tead1b ( Chr: 7 )
    CITATIONS (22)