ZFIN ID: ZDB-GENE-091012-1
Gene Name: solute carrier family 22 (organic cation/carnitine transporter), member 5
Gene Symbol: slc22a5
Previous Name: si:ch211-25g7.3
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 3 from Nilsson et al., 2009
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
  head, post-vent region
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-slc22a5 (1)

Allele Type Mutagen Suppliers
sa12067 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: Fig. 4 from Nilsson et al., 2009
    Observed in: heme biosynthetic process, nucleate erythrocyte hemoglobin complex, nucleate erythrocyte
    DISEASE ASSOCIATED WITH slc22a5 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    systemic primary carnitine deficiency disease Carnitine deficiency, systemic primary 212140
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heme biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane transporter activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005828 (1)
  • InterPro:IPR005829 (1)
  • InterPro:IPR020846 (1)
  • PROSITE:PS00216 (1)
  • PROSITE:PS50850 (1)
  • Pfam:PF00083 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc22a5-001 (1) 3729
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc22a5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slc22a5 Contained in: [BAC] CH211-25G7 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009295741 (1) 3046 bp
    Genomic GenBank:CU302316 (1) 166312 bp
    Select Tool
    Polypeptide UniProtKB:E7FAP2 (1) 549 aa
    Sequence Information (all 4)
    OTHER slc22a5 GENE PAGES
  • Gene:100000685 (1)
  • VEGA:OTTDARG00000034898 (1)
  • Ensembl(Zv9):ENSDARG00000068603 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish slc22a5 21  
    Human SLC22A5 5 (5q23.3)
  • OMIM:603377
  • Gene:6584
  • Mouse Slc22a5 11 ( 32.02 cM)
  • MGI:1329012
  • Gene:20520
  • Orthology Details
    CITATIONS (11)