ZFIN ID: ZDB-GENE-090918-4
Gene Name: dipeptidyl-peptidase 6a
Gene Symbol: dpp6a    Nomenclature History

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Previous Name: si:ch211-232k18.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (dipeptidyl peptidase like 6).
Genome Resources: Alliance (1),  Gene:100007104 (1),  Ensembl(GRCz11):ENSDARG00000076826 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44083 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44084 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dpp6a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability 33 Alliance Mental retardation, autosomal dominant 33 616311
    {Ventricular fibrillation, paroxysmal familial, 2} 612956
    DISEASE ASSOCIATED WITH dpp6a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function serine-type peptidase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dpp6a-201 (1)    Ensembl 2498
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dpp6a No data available
    MARKER RELATIONSHIPS
    dpp6a Contained in: [BAC] CH73-31L9 (1), CH73-289N8 (1), CH211-232K18 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009297267 (1)
    Genomic GenBank:BX890551 (1) 151758 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4ISU8 (1) 800 aa
    Sequence Information (all 24)
    ORTHOLOGY for dpp6a ( Chr: 24 )
    CITATIONS (15)