ZFIN ID: ZDB-GENE-090918-3
Gene Name: neuroligin 2b
Gene Symbol: nlgn2b    Nomenclature History

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Previous Name: nlgn2a (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to localize to the cell surface; integral component of plasma membrane; and synapse. Is expressed in several structures, including gill; gonad; heart; nervous system; and swim bladder. Orthologous to human NLGN2 (neuroligin 2).
Genome Resources: Alliance (1),  Gene:100002407 (1),  Ensembl(GRCz11):ENSDARG00000079251 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6171 Point Mutation Unknown Premature Stop ENU
sa9514 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nlgn2b
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nlgn2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nlgn2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component inhibitory synapse (more)
    Molecular Function neurexin family protein binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000460 Neuroligin
    Domain IPR002018 Carboxylesterase, type B
    Conserved_site IPR019819 Carboxylesterase type B, conserved site
    Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
    Family IPR030023 Neuroligin-2
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nlgn2b No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001166336 (1) 2583 bp
    Genomic GenBank:BX957271 (1) 161165 bp
    Select Tool
    Polypeptide UniProtKB:D0EVW9 (1) 860 aa
    Sequence Information (all 14)
    ORTHOLOGY for nlgn2b ( Chr: 10 )
    CITATIONS (20)