ZFIN ID: ZDB-GENE-090918-2
Gene Name: neuroligin 2a
Gene Symbol: nlgn2a    Nomenclature History

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Previous Names: nlgn2b, nlgn2bl

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Is expressed in digestive system; gill; gonad; heart; and nervous system. Orthologous to human NLGN2 (neuroligin 2).
Genome Resources: Alliance (1),  Gene:556158 (1),  Ensembl(GRCz11):ENSDARG00000077329 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh311 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ihb90 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb91 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb92 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la016034Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nlgn2a_unrecovered Point Mutation Unknown Unknown ENU
    sa16117 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26941 Point Mutation Unknown Premature Stop ENU
    sa30629 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40874 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40875 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nlgn2a
    2
    CRISPR2-nlgn2a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nlgn2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nlgn2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component cell junction (more)
    Molecular Function neurexin family protein binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nlgn2a-201 (1)    Ensembl 2433
    nlgn2a-202 (1)    Ensembl 6392
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nlgn2a No data available
    MARKER RELATIONSHIPS
    nlgn2a Contained in: [BAC] CH211-94B7 (1), DKEY-85K7 (1) (order this), DKEYP-101E9 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001166329 (1) 2433 nt
    Genomic GenBank:BX005336 (1) 233826 nt Blast at MegaBLAST
    Polypeptide UniProtKB:D2X2G0 (1) 828 aa
    Sequence Information (all 24)
    ORTHOLOGY for nlgn2a ( Chr: 7 )
    CITATIONS (31)